diff --git a/flask/helpers.py b/flask/helpers.py
index 1359bba6..dbbbf2e6 100644
--- a/flask/helpers.py
+++ b/flask/helpers.py
@@ -24,7 +24,6 @@ from functools import update_wrapper
 
 from werkzeug.datastructures import Headers
 from werkzeug.exceptions import NotFound
-import six
 from flask._compat import string_types, text_type
 
 # this was moved in 0.7
@@ -128,7 +127,7 @@ def stream_with_context(generator_or_function):
     # pushed.  This item is discarded.  Then when the iteration continues the
     # real generator is executed.
     wrapped_g = generator()
-    six.advance_iterator(wrapped_g)
+    next(wrapped_g)
     return wrapped_g
 
 
diff --git a/flask/json.py b/flask/json.py
index 6b95fde0..7777ba5d 100644
--- a/flask/json.py
+++ b/flask/json.py
@@ -11,13 +11,13 @@
 import uuid
 from datetime import datetime
 from .globals import current_app, request
+from ._compat import text_type
 
 from werkzeug.http import http_date
 
 # Use the same json implementation as itsdangerous on which we
 # depend anyways.
 from itsdangerous import json as _json
-import six
 
 
 # figure out if simplejson escapes slashes.  This behavior was changed
@@ -60,7 +60,7 @@ class JSONEncoder(_json.JSONEncoder):
         if isinstance(o, uuid.UUID):
             return str(o)
         if hasattr(o, '__html__'):
-            return six.text_type(o.__html__())
+            return text_type(o.__html__())
         return _json.JSONEncoder.default(self, o)
 
 
diff --git a/flask/templating.py b/flask/templating.py
index 754c6893..63adb092 100644
--- a/flask/templating.py
+++ b/flask/templating.py
@@ -15,7 +15,7 @@ from jinja2 import BaseLoader, Environment as BaseEnvironment, \
 from .globals import _request_ctx_stack, _app_ctx_stack
 from .signals import template_rendered
 from .module import blueprint_is_module
-import six
+from ._compat import itervalues, iteritems
 
 
 def _default_template_ctx_processor():
@@ -80,7 +80,7 @@ class DispatchingJinjaLoader(BaseLoader):
         except (ValueError, KeyError):
             pass
 
-        for blueprint in six.itervalues(self.app.blueprints):
+        for blueprint in itervalues(self.app.blueprints):
             if blueprint_is_module(blueprint):
                 continue
             loader = blueprint.jinja_loader
@@ -93,7 +93,7 @@ class DispatchingJinjaLoader(BaseLoader):
         if loader is not None:
             result.update(loader.list_templates())
 
-        for name, blueprint in six.iteritems(self.app.blueprints):
+        for name, blueprint in iteritems(self.app.blueprints):
             loader = blueprint.jinja_loader
             if loader is not None:
                 for template in loader.list_templates():
diff --git a/flask/testsuite/basic.py b/flask/testsuite/basic.py
index 85b758b1..485ed5fd 100644
--- a/flask/testsuite/basic.py
+++ b/flask/testsuite/basic.py
@@ -17,10 +17,10 @@ import unittest
 from datetime import datetime
 from threading import Thread
 from flask.testsuite import FlaskTestCase, emits_module_deprecation_warning
+from flask._compat import text_type
 from werkzeug.exceptions import BadRequest, NotFound
 from werkzeug.http import parse_date
 from werkzeug.routing import BuildError
-import six
 
 
 class BasicFunctionalityTestCase(FlaskTestCase):
@@ -276,7 +276,7 @@ class BasicFunctionalityTestCase(FlaskTestCase):
 
         @app.route('/test')
         def test():
-            return six.text_type(flask.session.permanent)
+            return text_type(flask.session.permanent)
 
         client = app.test_client()
         rv = client.get('/')
diff --git a/flask/testsuite/blueprints.py b/flask/testsuite/blueprints.py
index 89a8f2d7..97a196d7 100644
--- a/flask/testsuite/blueprints.py
+++ b/flask/testsuite/blueprints.py
@@ -13,10 +13,10 @@ import flask
 import unittest
 import warnings
 from flask.testsuite import FlaskTestCase, emits_module_deprecation_warning
+from flask._compat import text_type
 from werkzeug.exceptions import NotFound
 from werkzeug.http import parse_cache_control_header
 from jinja2 import TemplateNotFound
-import six
 
 
 # import moduleapp here because it uses deprecated features and we don't
@@ -303,7 +303,7 @@ class BlueprintTestCase(FlaskTestCase):
 
         @bp.route('/bar')
         def bar(bar):
-            return six.text_type(bar)
+            return text_type(bar)
 
         app = flask.Flask(__name__)
         app.register_blueprint(bp, url_prefix='/1', url_defaults={'bar': 23})
diff --git a/flask/testsuite/ext.py b/flask/testsuite/ext.py
index f6209c67..370a31d8 100644
--- a/flask/testsuite/ext.py
+++ b/flask/testsuite/ext.py
@@ -11,9 +11,12 @@
 
 import sys
 import unittest
+try:
+    from imp import reload as reload_module
+except ImportError:
+    reload_module = reload
 from flask.testsuite import FlaskTestCase
 from flask._compat import PY2
-from six.moves import reload_module
 
 class ExtImportHookTestCase(FlaskTestCase):
 
diff --git a/flask/testsuite/helpers.py b/flask/testsuite/helpers.py
index b76d36d1..d0054de1 100644
--- a/flask/testsuite/helpers.py
+++ b/flask/testsuite/helpers.py
@@ -15,8 +15,7 @@ import unittest
 from logging import StreamHandler
 from flask.testsuite import FlaskTestCase, catch_warnings, catch_stderr
 from werkzeug.http import parse_cache_control_header, parse_options_header
-import six
-from flask._compat import StringIO
+from flask._compat import StringIO, text_type
 
 
 def has_encoding(name):
@@ -34,7 +33,7 @@ class JSONTestCase(FlaskTestCase):
         app = flask.Flask(__name__)
         @app.route('/json', methods=['POST'])
         def return_json():
-            return six.text_type(flask.request.json)
+            return text_type(flask.request.json)
         c = app.test_client()
         rv = c.post('/json', data='malformed', content_type='application/json')
         self.assert_equal(rv.status_code, 400)
@@ -43,7 +42,7 @@ class JSONTestCase(FlaskTestCase):
         app = flask.Flask(__name__)
         @app.route('/json', methods=['POST'])
         def return_json():
-            return six.text_type(flask.request.json)
+            return text_type(flask.request.json)
         c = app.test_client()
         rv = c.post('/json', data='malformed', content_type='application/json')
         self.assert_equal(rv.status_code, 400)
@@ -95,7 +94,7 @@ class JSONTestCase(FlaskTestCase):
         app = flask.Flask(__name__)
         @app.route('/add', methods=['POST'])
         def add():
-            return six.text_type(flask.request.json['a'] + flask.request.json['b'])
+            return text_type(flask.request.json['a'] + flask.request.json['b'])
         c = app.test_client()
         rv = c.post('/add', data=flask.json.dumps({'a': 1, 'b': 2}),
                             content_type='application/json')
@@ -506,7 +505,7 @@ class StreamingTestCase(FlaskTestCase):
             def close(self):
                 called.append(42)
             def next(self):
-                return six.advance_iterator(self._gen)
+                return next(self._gen)
         @app.route('/')
         def index():
             def generate():
diff --git a/flask/testsuite/testing.py b/flask/testsuite/testing.py
index e7206d21..cd96b497 100644
--- a/flask/testsuite/testing.py
+++ b/flask/testsuite/testing.py
@@ -12,7 +12,7 @@
 import flask
 import unittest
 from flask.testsuite import FlaskTestCase
-import six
+from flask._compat import text_type
 
 
 class TestToolsTestCase(FlaskTestCase):
@@ -84,7 +84,7 @@ class TestToolsTestCase(FlaskTestCase):
 
         @app.route('/')
         def index():
-            return six.text_type(flask.session['foo'])
+            return text_type(flask.session['foo'])
 
         with app.test_client() as c:
             with c.session_transaction() as sess:
diff --git a/setup.py b/setup.py
index 1d3e36ad..ddc83251 100644
--- a/setup.py
+++ b/setup.py
@@ -91,7 +91,6 @@ setup(
     zip_safe=False,
     platforms='any',
     install_requires=[
-        'six>=1.3.0',
         'Werkzeug>=0.7',
         'Jinja2>=2.4',
         'itsdangerous>=0.17'